Endocrine Abstracts

BackgroundCardiovascular complications of Cushing’s syndrome (CS) include; hypertension, left ventricular hypertrophy, and myocardial ischaemia. Also, CS can cause structural and functional changes in the heart, leading to dilated cardiomyopathy in rare cases. Here, we present a case with dilated cardiomyopathy related to Cushing’s syndrome.CaseA 31-year-old male patient applied to the cardiology de...

It is known that disoaders of the hypothalamic-pituitary-adrenal system and excess glucocorticoids in Cushing’s disease (CD) can significantly affect various organs and systems, in particular, the secretion of pituitary hormones. However, in the literature there is practically no work on the assessment of the state of tropic hormones and hormones of the peripheral glands in the early postoperative period after transsphenoidal adenomectomy. The aim of this study was to ass...

Introduction: Subclinical Cushing’s syndrome refers to autonomous cortisol secretion in patients who do not have the typical signs and symptoms of hypercortisolism. This study was undertaken to describe clinical, biological and radiological features of this disease and to evaluate the clinical outcome after surgical and medical treatment.Methods: Retrospective study conducted over a period of 12 years and including 17 patients hospitalised in our de...

Introduction: Cushing’s disease is diabetogenic due to the insulin resistance generated by the stimulating effect of glucocorticoids on neoglucogenesis and hepatic glycogenolysis.GoalAim of our work is to study the frequency and characteristics of diabetes mellitus during Cushing’s disease.Material and Methods: Retrospective study of a sample of 100 patients collected between (January 1983 –...

Hyperthyroidism in Graves’ disease (GD) is caused by thyroid-stimulating autoantibodies to the TSH receptor. Hypothyroidism in Hashimoto’s thyroiditis (HT) is associated with thyroid peroxidase and thyroglobulin autoantibodies. Transformation of HT to GD has been rarely reported. We report a woman with history of HT, who then developed GD.Case presentation: A 50-year-old female with a past history of hypothyroidism due to HT treated with Levo...

Cushing’s syndrome is a rare endocrine disorder which the Royal College of Physicians/Society for Endocrinology Guidelines – Pituitary Tumours (1997) suggest should only be differentially diagnosed in centres with appropriate technical and enocrinological expertise. We conducted an audit against these guidelines of the management of Cushing’s syndrome in our unit (population covered 250, 000) over the 3-year period between January 2003 and January 2006. Aetiolog...

IntroductionFahr’s syndrome (FS) is a rare neurodegenerative disorder. It’s characterized by abnormal calcifications in basal ganglia and cerebral cortex inducing neuropsychiatric disorders and cognitive impairment. The aim of our study was to assess the prevalence of FS, its characteristics, and its associated factors in patients with permanent hypoparathyroidism.MethodsWe conducted a cross-section...

Objective: To evaluate the monitoritation systems acceptance: capillary glucose measurements and continuous glucose sensors (CGSM and GUARDIAN).Research design and methods: 15 diabetics patients were monitoritatied in two diferents periods of time. (Period 1: Guardian, 86 hours long. Period 2: CGSM 72 hours long). Later, they had to fill a satisfaction questionnaire concerning several aspects which were valued from 0–6.<table boarder="1" cellpad...

ContextThe occurrence of different subtypes of endogenous Cushing’s syndrome (CS) in single individuals is extremely rare. We here present the case of a female patient who was successfully cured from adrenal CS 4 years before being diagnosed with Cushing’s disease (CD).Case DescriptionA 50-year-old female was diagnosed with ACTH-independent CS and a left-sided adrenal adenoma in January 2015. After ...

Context: The occurrence of different subtypes of endogenous Cushing’s syndrome (CS) in single individuals is extremely rare. We here present the case of a female patient who was successfully cured from adrenal CS 4 years before being diagnosed with Cushing&apos;s disease (CD).Case Description: A 50-year-old female was diagnosed with ACTH-independent CS and a left-sided adrenal adenoma in January 2015. After adrenalectomy and histopathological co...